. 2019 Dec 12;10(3):159–167. doi: 10.34172/bi.2020.20

Table 3. Effects of various doses of HESS, GB and GB plus HESS on PON1, lipid peroxidation and the inflammatory factors in experimental groups .

Groups	Parameters
Groups	PON1 (µU/L)	MDA (µM/mL)	TNF-α (PM/mL)	hs -CRP (ng/mL)
NC^a	143.6±6^b	0.021±0.002^b-h	19.8±1.1^b,c	1.8±0.3^b,c
DC^b	80.2±16^a,d-h	0.039±0.002^a,d,e,g,h	21.6±1.3^a,d,f,g	2.4±0.3^a,e-d
HESS-100^c	82.2±17^a,d-h	0.039±0.002^a,d,e,g,h	21.7±1.7^a,d,g,h	2.29±0.3^a,d,e,g,h
HESS-200^d	121.0±16^b,c,h	0.034±0.002^a-c,e,h	20.4±.9	1.81±0.4^b,c
HESS-400^e	126.0±6^b,c	0.029±0.002^a-d,f,g	19.6±1.2^b,c	1.78±0.2^b,c
GB^f	140.0±6^b,c	0.035±0.002^a-c,e,g,h	20.2±1.0	1.91±0.4^b
GB+HESS-200^g	143.2±7^b,c	0.034±0.001^a-c,e,h	19.6±1.0^b,c	1.79±0.2^b,c
GB+HESS-400^h	146.60±10^b-d	0.029±0.002^a-d,f,g	18.8±1.1^b,c	1.73±0.1^b,c
ANOVA ( P value)	0.001	0.001	0.013	0.016

The variables are presented as means ± SD. NC (normal control); DC (diabetic control); HESS (hydroalcoholic extract of S. securidaca seeds); GB (glibenclamide).Groups at the left column have been defined by superscript letters (^a–^h). Superscript letters (^a–^f) within a column denote significant differences ( P < 0.05).