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. 2020 Jul 6;41(13):3567–3579. doi: 10.1002/hbm.25030

FIGURE 3.

FIGURE 3

Sex differences and classification results using regional volume. (a) Region‐wise sex differences in volume for the CC400 atlas. Lateral (top) and medial (bottom) sides of the left (LH) and right (RH) hemispheres are shown. Regional t‐statistics are shown as per the color scale for all significantly different (p‐corrected <.05) areas. Nonsignificant areas are shown in grey. A positive t‐statistic indicates that males have a higher mean value in that region than females. (b) Receiver operating characteristic curves for linear support vector machine (SVM) sex classification for all atlases based on volume. Mean and SD of the area under the curve (AUC) values for each atlas are indicated. (c) Feature importance map for a linear support vector machine (SVM) classifier used to predict sex using volume of each region in the CC400 atlas. Lateral (top) and medial (bottom) sides of the left (LH) and right (RH) hemispheres are shown. The absolute value of feature weights obtained from the linear SVM were scaled to generate normalized feature importance values. Values closer to 1 indicate greater importance in the overall classification