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Systemic immune response after a single vaccination. Serum IgG responses were evaluated 30 days after a single immunization with the indicated amounts of WIV. IgG titers are presented as log10 titers for individual cotton rats with means per group (n = 4). LoD is indicated at 2 with a dashed line and significance is represented as *P < .05. IgG, immunoglobulin; LOD, limit of detection; PBS, phosphate‐buffered saline; WIV, whole inactivated virus
