Figure 7.
Effect of prime/boost vaccination on lung virus titers after challenge. Thirty days after the second vaccination, cotton rats were challenged with 107 TCID50 homologous A/Cal/Gro by i.n. administration. One day post‐challenge, lung virus titers were determined by TCID50. Virus titers of individual animals and the mean virus titer per experimental group are depicted. Significance is represented as *P < .05. LoD for the virus titers is indicated at 0.3 with a dashed line. LOD, limit of detection