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. 2020 Aug 1;2020:9761878. doi: 10.1155/2020/9761878

Table 2.

Clinical characteristics and inflammation biomarkers in the training cohort. Data are shown as the mean ± SD or median (P25 and P75).

Variable Training cohort
Sepsis (-), n = 467 Sepsis (+), n = 55
Age 55.41 ± 13.05 59.29 ± 11.24 0.02
Sex
 Male 305 34 0.61
 Female 162 21
Perioperative blood transfusion
 Yes 165 38 ≤0.001
 No 302 17
ASA scores
 1 10 1 ≤0.001
 2 392 42
 3 64 11
 4 1 1
Diabetes
 Yes 78 17 0.01
 No 389 38
BMI 23.5 ± 3.21 24.69 ± 3.12 0.01
Operative time (min) 280 (210-340) 345 (262.5-431) 0.03
Intraoperative blood loss 300 (200-600) 400 (200-800)
Preoperative ALT 44 (20.45-122.5) 62 (24.5-104.9) 0.53
Preoperative AST 35.6 (20.85-98.95) 42.6 (26.4-81.9) 0.47
Preoperative direct bilirubin 5.1 (3.2-31) 35.5 (5.1-132.05) ≤0.001
Inflammation biomarkers
 IL-1 (pg/ml) 5 (5-5) 5 (5-5) 0.46
 IL-2 (U/ml) 767 (600-1023) 1034 (699.5-1378.5) ≤0.001
 IL-6 (pg/ml) 82.2 (46.15-164.5) 171 (102-274) ≤0.001
 IL-8 (pg/ml) 89 (40.2-190) 105 (55.55-242) 0.18
 IL-10 (pg/ml) 5.78 (5-10) 9.56 (5.86-14.35) ≤0.001
 TNF-α (pg/ml) 16.3 (11-30.55) 16.5 (10.5-24.95) 0.50
 PCT (ng/ml) 0.55 (0.28-1.01) 1.53 (0.809-3.29) ≤0.001
 CRP (mg/dl) 3.73 (1.96-6.29) 6.62 (4.62-9.35) ≤0.001
 NLR 11.1 (7.73-15.73) 12.17 (8.10-16.94) 0.39