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. 2020 Aug 1;2020:8894168. doi: 10.1155/2020/8894168

Figure 1.

Figure 1

Antihypertensive medications alter the secretome of monocytes from healthy controls and stroke patients after 24 hours of exposure. Atenolol (a–d) increased IL-1RA and TNF-α secretions from stroke patient-derived monocytes but reduced the IL-1RA and MCP-1 secretions from health control monocytes. Captopril (e–h) increased IL-1RA secretions from stroke patient-derived monocytes but increased IL-8 secretions from both healthy control and stroke monocytes. Losartan (i–l) did not alter cytokine secretions from stroke patient-derived monocytes but reduced MCP-1 secretions from healthy control monocytes. Significance is shown by ∗p < 0.05. All fold changes are as compared to vehicle control.