Table 1.
Survivors | Nonsurvivors | Control | P value | |
---|---|---|---|---|
n = 35 | n = 36 | n = 17 | ||
APACHE-II score | 19.0 (13.0-25.0) | 26.0 (20.0-32.0) | <0.001a | |
SOFA score | 9.0 (6.0-11.0) | 13.0 (10.0-15.0) | <0.001a | |
Procalcitonin (ng/L) | 2.9 (0.5-12.9) | 13.1 (2.8-33.0) | 0.009a | |
C-reactive protein (mg/L) | 169.0 (87.8-302.5) | 178.6 (98.9-283.1) | 1.2 (0.4-1.9) | 1.00a |
<0.001b,c | ||||
White blood cells (103/μL) | 15.0 (11.0-21.8) | 15.1 (10.7-21.2) | 0.875a | |
Haemoglobin (g/dL) | 10.2 (8.2-11.6) | 9.5 (8.6-10.7) | 0.945a | |
Fibrinogen (g/L) | 5.2 (4.1-6.5) | 5.2 (2.9-5.7) | 0.279a | |
pFN (mg/L) | 152.8 (114.5-164.2) | 106.0 (63.7-149.4) | 231.2 (191.2-273.2) | 0.004a |
<0.001b,c | ||||
EDA-FN (mg/L) | 6.7 (3.8-20.5) | 9.4 (2.6-20.3) | 1.4 (0.9-1.6) | 1.00a |
<0.001b,c | ||||
ICU free days to day 28 | 18 (9–21) | 20 (9–24) | 0.103a |
APACHE II: Acute Physiology and Chronic Health Evaluation II; SOFA: Sequential Organ Failure Assessment; pFN: plasma fibronectin; EDA-FN: extra domain A fibronectin; ICU: intensive care unit. The comparison of continuous variables between two independent groups (nonsurvivors vs. survivors) was performed using the Mann-Whitney U test. The comparison of continuous variables across three groups (nonsurvivors, survivors, control) was performed using the Kruskal-Wallis test, and a post hoc was used to compare subgroups. The P value represents statistically significant differences calculated between the following groups: anonsurvivors vs. survivors, bnonsurvivors vs. control, csurvivors vs. control.