Figure 6.

Exploring genetic alterations in THBS1, FN1, CALM1, COL4A1, CTGF, and IGFBP5 in GC by cBioPortal: (a) summary of changes within THBS1, FN1, CALM1, COL4A1, CTGF, and IGFBP5 genes in genomics datasets available for stomach adenocarcinoma (TCGA, Provisional) studies; (b) OncoPrint: a visual summary of alterations across a set of stomach adenocarcinoma samples (data are taken from TCGA Data Portal) based on a query of the 6 genes (THBS1, FN1, CALM1, COL4A1, CTGF, and IGFBP5). Distinct genomic alterations are summarized, color-coded, and presented as percent changes in particularly affected genes in individual tumor samples. Each row represents a gene, and each column represents a tumor sample. Green squares indicate missense mutations; black represents truncating mutations; red bars designate gene amplifications; blue bars represent deep deletions, and grey signifies no alterations.