Table 1.
Baseline characteristics of the study population, according to treatment group.
| CEA (n = 203) | CAS (n = 197) | BMT (n = 113) | Total (n = 513) | |
|---|---|---|---|---|
| Male sex (% of patients) | 151 (74.4%) | 143 (72.6%) | 87 (77.0%) | 381 (74.3%) |
| Age (years, median (IQR)) | 70 (64, 75) | 70 (63, 75) | 68 (64, 74) | 70 (64, 75) |
| Side randomized: left | 105 (51.7%) | 105 (53.3%) | 49 (43.4%) | 259 (50.5%) |
| Ipsilateral symptomsa | 16 (7.9%) | 8 (4.1%) | 5 (4.4%) | 29 (5.7%) |
| Grade of stenosisb (median (IQR)) | 80 (75, 85) | 80 (75, 85) | 80 (75, 85) | 80 (75, 85) |
| Grade of contralateral stenosisb | 20 (0, 50) | 30 (0, 60) | 10 (0, 55) | 20 (0, 55) |
| Contralateral occlusion | 3 (1.5%) | 12 (6.1%) | 3 (2.7%) | 18 (3.5%) |
| Systolic BPc (median (IQR)) | 147 (131, 160) | 145 (130, 162) | 150 (133, 160) | 146 (130, 160) |
| Diastolic BPc (median (IQR)) | 80 (72, 88) | 80 (74, 90) | 80 (75, 89) | 80 (73, 89) |
| Hypertension (% of patients) | 180 (88.7%) | 177 (89.8%) | 102 (90.3%) | 459 (89.5%) |
| Diabetes | 52 (25.6%) | 59 (29.9%) | 40 (35.4%) | 151 (29.4%) |
| Coronary heart disease | 70 (34.5%) | 72 (36.5%) | 40 (35.4%) | 182 (35.5%) |
| Hypercholesterolemia | 158 (77.8%) | 158 (80.2%) | 91 (80.5%) | 407 (79.3%) |
| Current smoker | 45 (22.2%) | 31 (15.7%) | 24 (21.2%) | 100 (19.5%) |
| Past smoker | 91 (44.8%) | 99 (50.3%) | 67 (59.3%) | 257 (50.1%) |
| Cholesterold (median (IQR)) | 181 (153, 209) | 173.5 (152, 200) | 169.5 (146.5, 192.5) | 174 (151, 203) |
| Glucosed (median (IQR)) | 103.5 (92, 121) | 104 (93, 125) | 104 (92, 119) | 104 (92.5, 122) |
| HbA1c in % (median (IQR)) | 6 (5.7, 6.45) | 6 (5.7, 6.6) | 5.9 (5.55, 6.75) | 6 (5.7, 6.5) |
| Number of vascular risk factors | 2 (2, 3) | 3 (2, 3) | 3 (2, 3) | 3 (2, 3) |
| HDLd (median (IQR)) | 48 (40, 62) | 49 (40, 56.5) | 49 (41.5, 57.5) | 49 (41, 58) |
| LDLd (median (IQR)) | 105 (81, 130) | 98.5 (80, 126) | 97 (80, 117) | 99 (80, 123.5) |
| Triglycerided (median (IQR)) | 131 (98, 182.5) | 128.5 (92, 184) | 120 (91, 181) | 126.5 (94, 182) |
| BMI (median (IQR)) | 27 (25, 30) | 27 (25, 30) | 27 (24, 29) | 27 (25, 30) |
| Time delaye (median (IQR)) | 14 (8, 21) | 14 (8, 21) | – | 14 (8, 21) |
Note: Continuous variables are given as medians with interquartile range (lower and upper quartiles), and as n (%) for categorical variables. Dashes indicate not applicable; IQR: interquartile range; CAS: carotid artery stenting; BMT: best medical treatment; CEA: carotid endarterectomy; BP: blood pressure; BMI: body mass index; HDL: High-densitiy lipoprotein; LDL: Low-density lipoprotein.
a
>180 days on side of randomized carotid artery.
b
% ECST.
c
BP in mm Hg.
d
mg/dl.
e
Time from randomization to treatment (days).