Table 3.
Endpoint event rates (95% confidence interval) within the first year; n = 513.
| CEA (n = 203) | CAS (n = 197) | BMT (n = 113) | p | |
|---|---|---|---|---|
| One-year major secondary endpoint (n = 12) | 5 (2.5%; 0.8%–5.7%) | 6 (3.0%; 1.1%–6.5%) | 1 (0.9%; 0.0%–4.8%) | 0.530± |
| Any stroke (n = 17) | 8 (3.9%; 1.7%–7.6%) | 8 (4.1%; 1.8%–7.8%) | 1 (0.9%; 0.0%–4.8%) | 0.256± |
| Any stroke after d30a (n = 7) | 3 (1.5%; 0.3%–4.3%) | 3 (1.5%; 0.3%–4.4%) | 1 (0.9%; 0.0%–4.8%) | 1.000± |
| Ipsilateral stroke (n = 11) | 4 (2.0%; 0.5%–5.0%) | 6 (3.0%; 1.1%–6.5%) | 1 (0.9%; 0.0%–4.8%) | 0.497± |
| Ipsilateral stroke after d30a (n = 2) | 0 (0.0%; 0.0%–1.8%) | 1 (0.5%; 0.0%–2.8%) | 1 (0.9%; 0.0%–4.8%) | 0.521± |
| Disabling strokeb (n = 4) | 2 (1.0%; 0.1%–3.5%) | 1 (0.5%; 0.0%–2.8%) | 1 (0.9%; 0.0%–4.8%) | 1.000± |
| Any death (n = 11) | 5 (2.5%; 0.8%–5.7%) | 2 (1.0%; 0.1%–3.6%) | 4 (3.5%; 1.0%–8.8%) | 0.304± |
| Myocardial infarction (n = 1) | 1 (0.5%; 0.0%–2.7%) | 0 (0.0%; 0.0%–1.9%) | 0 (0.0%; 0.0%–3.2%) | 1.000± |
| Restenosisc (n = 15) | 4 (2.0%; 0.5%–5.0%) | 11 (5.6%; 2.8%–9.8%) | – | 0.068± |
| Rec- or progressived stenosis (n = 20) | 4 (2.0%; 0.5%–5.0%) | 11 (5.6%; 2.8%–9.8%) | 5 (4.4%; 1.5%–10.0%) | 0.158± |
| TIA (n = 15) | 4 (2.0%; 0.5%–5.0%) | 5 (2.5%; 0.8%–5.8%) | 6 (5.3%; 2.0%–11.2%) | 0.230± |
| Ipsilateral TIA (n = 12) | 2 (1.0%; 0.1%–3.5%) | 4 (2.0%; 0.6%–5.1%) | 6 (5.3%; 2.0%–11.2%) | 0.063± |
Note: Dashes indicate not applicable. CAS: carotid artery stenting; BMT: best medical treatment; CEA: carotid endarterectomy; ± : Fisher's exact test; TIA: transient ischemic attack; if 0%: Confidence interval one-sided 97.5%.
a
After intervention for CEA/CAS and after randomization for BMT.
b
mRS 30 days after stroke > 2.
c
Only in CEA and CAS.
d
Only in BMT.