Table I.
Correlation between ECT2 positivity and clinicopathological characteristics of patients with gastric cancer (n=130).
| Characteristics | Total n=130 | ECT2 strong positivity, n=35 | ECT2 weak positivity/absent, n=95 | P-value |
|---|---|---|---|---|
| Age, years | 0.241 | |||
| <60 | 67 | 21 | 46 | |
| ≥60 | 63 | 14 | 49 | |
| Sex | 0.077 | |||
| Male | 93 | 21 | 72 | |
| Female | 37 | 14 | 23 | |
| Tumor localization | 0.091 | |||
| Cardias | 20 | 7 | 13 | |
| Body | 40 | 15 | 25 | |
| Antrum | 52 | 8 | 44 | |
| Whole/Multiple | 18 | 5 | 13 | |
| Histology | 0.216 | |||
| ADC, WD | 19 | 5 | 14 | |
| ADC, MD | 42 | 7 | 35 | |
| ADC, PD | 48 | 19 | 29 | |
| Signet ring cell | 14 | 3 | 11 | |
| Mucinous adenocarcinoma | 6 | 1 | 5 | |
| Neuroendocrine carcinoma | 1 | 0 | 1 | |
| TNM stage | <0.001 | |||
| I + II | 67 | 8 | 59 | |
| III + IV | 63 | 27 | 36 | |
| pT (Tumor invasion) | 0.039 | |||
| T1 + T2 | 22 | 2 | 20 | |
| T3 + T4 | 108 | 33 | 75 | |
| pN (Lymph node metastasis) | 0.896 | |||
| N0 | 42 | 11 | 31 | |
| N1-N3 | 88 | 24 | 64 | |
| pM (Distant metastasis) | 0.473 | |||
| M0 | 114 | 29 | 85 | |
| M1 | 16 | 6 | 10 |
ECT2, epithelial cell transforming 2; ADC, adenocarcinoma; WD, well differentiated; MD, moderately differentiated; PD, poorly differentiated; TNM, tumor-node-metastasis.