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Tumor-bearing mice survival following inhibition of glutamine metabolism. a–c Mice survival following orthotopic injection of M1 (a), M2 (b), and CNP1 (c) primary cells. CB839 (CB, 20 μM) was injected orthotopically in the mice brain 1 h after primary GBM cell injection. EGCG (110 μM) was added to cell culture 6 days prior to orthotopic injection of tumor cells. Log rank test, *p < 0.05, **p < 0.01, ***p < 0.001
