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. 2020 Feb 10;185(5):843–865. doi: 10.1007/s11046-020-00431-2

Table 1.

Selected areas of Histoplasma endemicity outside the North America based on the histoplasmin skin reactivity

Country, year, region Number tested (population) Histoplasmin skin test positivity (%), (location if multiple in study)
Africa
 Mali, 1969 [304] 1253 (school children) 6.0
 Nigeria, 2018 [50] 735 (HIV-infected patients) 0 (Lagos), 3 (Yola), 2 (Ilorin), 6 (Calabar), 3 (Ibadan), 15 (Benin)
 Nigeria, Anambra State, 1996 [51] 40 (cave guides, traders, farmers near a cave), 620 (traders, farmers, palm oil workers)

35.0

8.8

 Nigeria, 1991 [305] 1087 (healthy subjects), 226 (pulmonary hospital patients)

1.7-5.0 (Hcc), 0.5-4.5 (Hcd)

8.9 (Hcc), 6.6 (Hcd)

 Somalia, Mogadishu and Jilib, 1979 [52] 1014 (NA) 0.3
 Uganda, 1970 [53] 1114 (residents) 3.9
Asia
 Bangladesh, 1971 [67] 2572 (pulmonary disease patients) 17.9
 China, 2001 [68] 735 (hospitalized patients and healthy residents) 8.9 (Hunan), 15.1 (Jiangsu), 2.1 (Xinjiang)
 China, Sichuan Province, 1996 [306]

271 (healthy students and workers)

28 (hospitalized TB patients)

21.8

28.6

 India, 1955 [61] 962 (NA) 1.9
 India, Delhi, 1962 [61] 8062 (NA) 6.8
 India, Kolkata (Calcutta), 1956 [61] 4855 (NA) 0.7
 Indonesia, 1956 [75] 2542 (students, hospital patients, nurses) 2.7 (children), 9–12 (adults), Jakarta
 Indonesia, 1956 [307] 281 in Surabaya, 340 in Kedisan (school children/villagers) 32 (Surabaya), 63.6 (Kedisan)
 Indonesia, Medan, 1997 [308] 1265 medical students 13.6
 Malaysia, Sarawak, 1963 [309] 181 school children/hospitalized patients 0.5
 Malaysia, Kuala Lumpur, 1964 [310] 224 adults 10.5
 Malaysia, Sabah, 1971 [76] 3824 (residents) 11.8
 Myanmar, 1952 [96] 3558 (prisoners)

14.5-27.1 (Lower and Rangoon), 4.0–8.4 (Upper)

86.4 (Maguee)

 Philippines, Luzon Island, 2001, 1964 [74] 143 (electric company employees) 25.9
 Philippines, Manilla, 1964 [311] 2577 (naval recruits) 6.4
 Thailand, 1966-1968, [312] NA (NA) 3–9 (central), 7–14 (northern), 15–36 (southeast and southern)
 Thailand, Bangkok, 1967 [313] 497 (medical/nursing students) 5.6
 Thailand, 1968 [73] 4211 (prisoners) 14 (northern), 9 (central), 36 (southern)
 Vietnam, 1956, Saigon [307] 303 school children/villagers 33.7
Caribbean
 Barbados, 1981 [314] 103 (NA) 4
 Trinidad, 1981 [314] 86 (NA) 42
Central and South America
 Argentina, San Martin City, 1996 [315] 315 (children) 9.2
 Belize, 1978 [316] 141 (NA) 40
 Brazil, Amazon, 1994 [317] NA (Tupi-Monde Amerindian populations) 78.7 (Surui), 5.8 (Gaviao), 80.5 (Zoro)
 Brazil, Recife, 1966 [318] 1006 (hospital patients) 20.5
 Brazil, Belem, 1966 [318] 258 (hospital patients and medical students) 43.4
 Brazil, Minas Gerais State, 1996 [319] 417 (miners) 17.5
 Colombia, 1968[320] NA (NA) 21.0
Guatemala, 1960 [321] 821 (hospital patients) 23–81
 Mexico, Guerrero State, 1997 [322] 139 (cave guides, guano collectors, fishermen) 87.3 (Jutlahuaca), 76.9 (Olinala), 3.8 (Coyuca)
 Venezuela, Bolivar State, 2004 [323] 157 (residents, farmers) 42.7
Europe
 Italy, Po Valley, 1994 [109] 776 (students) 1.2

Hcc—Histoplasma capsulatum var. capsulatum; HcdHistoplasma capsulatum var. duboisii; NA—information not available