Table 2.
Locus | Chr | Lead SNP | A1/A2 | Nearest Gene | Functional category | P-value SCZ | Odds ratio SCZ | P-value PD | Z-score PD | condFDR |
---|---|---|---|---|---|---|---|---|---|---|
42 | 5 | rs9293740 | A/G | RNU6–183P | upstream | 5.81E-06 | 0.95 | 9.27E-04 | −3.31 | 8.16E-03 |
The most strongly associated SNP in the novel genomic locus associated with SCZ at condFDR<0.01 given association with PD after merging regions < 250 kb apart into a single locus. The table presents chromosomal position (Chr), nearest gene and functional category, as well as p-values and effect sizes (odds ratios or z-scores) from the original summary statistics on SCZ and PD. The effect sizes are given with reference to allele 1 (A1). For more details and the full list of all loci associated with SCZ at condFDR<0.01, see Supplemental Table 4. See Supplemental Table 6 for all genes mapped to this locus.