Table 2. Differentially expressed genes based on critical points.

Thousands of genes are differentially expressed across critical points in the transcriptome state-transition from health to leukemia (q<0.05, |log2(FC)|>1).

Test vs. reference	#genes down	#genes up	#genes total
c1 vs control (${\mathit{c}}_{\mathbf{1}}^{*}$)	2,305	1,859	4,164
c2 vs control (${\mathit{c}}_{\mathbf{1}}^{*}$)	4,421	4,126	8,547
c3 vs control (${\mathit{c}}_{\mathbf{1}}^{*}$)	6,119	5,515	11,634
c2 vs c1	3,560	3,772	7,332
c3 vs c1	5,744	5,565	11,309
c3 vs c1	3,602	3,274	6,876