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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Neurocrit Care. 2020 Jun;32(3):697–706. doi: 10.1007/s12028-020-00944-0

Table 1.

Clinical and demographic variables.

All patients (n=143) EAs present a (n=67) EAs absent (n=76) P value

Age: median, (IQR) 66 (54–77.5) 67 (56.5–77.8) 66 (49–77.5) 0.37

Gender: F (%) 71 (49.7%) 34 (50.8%) 37 (48.7%) 0.81

Apache II: median, (IQR) 21 (15–26) 20 (14.3–25.8) 21 (15–26) 0.78

NIHSS: median, (IQR) 10 (6–17) 10 (6.3–18.5) 10.5 (6–16.5) 0.97

CCI: median, (IQR) 4 (2–6.8) 4 (3–7) 4 (2–6) 0.18

Stroke Etiology
Large Artery 48 (33.6%) 19 (28.4%) 29 (38.2%) 0.19
Embolic 62 (43.4%) 30 (44.8%) 32 (42.1%)
Small vessel 6 (4.2%) 1 (1.5%) 5 (6.6%)
Other etiology 12 (8.4%) 7 (10.5%) 5 (6.6%)
Cryptogenic 15 (10.5%) 10 (14.9%) 5 (6.6%)

Stroke location
Cortical 115 (80.4%) 56 (83.6%) 59 (77.6%) 0.41
Subcortical 28 (19.6%) 11 (16.4%) 17 (22.4%)
Anterior circulation 78 (54.6%) 40 (59.7%) 38 (50.0%) 0.43
Posterior circulation 29 (20.3%) 11 (16.4%) 18 (23.7%)
Multiple vascular territories 36 (25.2%) 16 (23.9%) 20 (26.3%)
Temporal 57 (39.9%) 33 (49.3%) 24 (31.6%) 0.04
Extra-temporal 86 (60.1%) 34 (50.8%) 52 (68.4%)

Thrombolytic treatment/Stroke intervention 16 (11.2%) 5 (7.5%) 11 (14.5%) 0.29

History of epilepsy 17 (11.9%) 11 (16.4%) 6 (7.9%) 0.13

Clinical seizure on presentation 23 (16.1%) 15 (22.4%) 8 (10.5%) 0.07

Clinical seizure during duration of hospital admission 29 (20.3%) 21 (31.4%) 8 (10.5%) 0.003

cEEG duration in hours: median (IQR) 44.8 (27.3–71.3) 59.7 (40.4–86.5) 39.2 (25.3 – 46.5) <0.0001

Anti-epileptic drugs 89 (62.2%) 56 (83.6%) 33 (43.4%) <0.0001

Cerebral edema 35 (24.5%) 19 (28.4%) 16 (21.1%) 0.34

Hemorrhagic transformation 21 (14.7%) 10 (14.9%) 11 (14.5%) 1.00

Hemicraniectomy 12 (8.4%) 7 (10.5%) 5 (6.6%) 0.55

Hospital acquired infections 63 (44.1%) 24 (35.8%) 39 (51.3%) 0.07

Duration of MV(days): median (IQR) 3 (0–7) 4 (0–8) 2 (0–6) 0.51

Length of stay (days): Median (IQR) 14 (7.5–25) 14 (8–26) 14 (7–21.5) 0.27

Discharge mortality 36 (25.2%) 20 (29.9%) 16 (21.1%) 0.25
Withdrawal of care 33 (91.7%) 19/20 (95.0%) 14/16 (87.5%)
a)

EAs excluding GRDA

APACHE II: Acute Physiology and Chronic Health Evaluation II; CCI: Charlson Comorbidity Index; cEEG: continuous electroencephalography; EAs: epileptiform abnormalities; MV: mechanical ventilation; NIHSS: National Institute of Health Stroke Scale