Table 1.
All patients (n=143) | EAs present a (n=67) | EAs absent (n=76) | P value | |
Age: median, (IQR) | 66 (54–77.5) | 67 (56.5–77.8) | 66 (49–77.5) | 0.37 |
Gender: F (%) | 71 (49.7%) | 34 (50.8%) | 37 (48.7%) | 0.81 |
Apache II: median, (IQR) | 21 (15–26) | 20 (14.3–25.8) | 21 (15–26) | 0.78 |
NIHSS: median, (IQR) | 10 (6–17) | 10 (6.3–18.5) | 10.5 (6–16.5) | 0.97 |
CCI: median, (IQR) | 4 (2–6.8) | 4 (3–7) | 4 (2–6) | 0.18 |
Stroke Etiology | ||||
Large Artery | 48 (33.6%) | 19 (28.4%) | 29 (38.2%) | 0.19 |
Embolic | 62 (43.4%) | 30 (44.8%) | 32 (42.1%) | |
Small vessel | 6 (4.2%) | 1 (1.5%) | 5 (6.6%) | |
Other etiology | 12 (8.4%) | 7 (10.5%) | 5 (6.6%) | |
Cryptogenic | 15 (10.5%) | 10 (14.9%) | 5 (6.6%) | |
Stroke location | ||||
Cortical | 115 (80.4%) | 56 (83.6%) | 59 (77.6%) | 0.41 |
Subcortical | 28 (19.6%) | 11 (16.4%) | 17 (22.4%) | |
Anterior circulation | 78 (54.6%) | 40 (59.7%) | 38 (50.0%) | 0.43 |
Posterior circulation | 29 (20.3%) | 11 (16.4%) | 18 (23.7%) | |
Multiple vascular territories | 36 (25.2%) | 16 (23.9%) | 20 (26.3%) | |
Temporal | 57 (39.9%) | 33 (49.3%) | 24 (31.6%) | 0.04 |
Extra-temporal | 86 (60.1%) | 34 (50.8%) | 52 (68.4%) | |
Thrombolytic treatment/Stroke intervention | 16 (11.2%) | 5 (7.5%) | 11 (14.5%) | 0.29 |
History of epilepsy | 17 (11.9%) | 11 (16.4%) | 6 (7.9%) | 0.13 |
Clinical seizure on presentation | 23 (16.1%) | 15 (22.4%) | 8 (10.5%) | 0.07 |
Clinical seizure during duration of hospital admission | 29 (20.3%) | 21 (31.4%) | 8 (10.5%) | 0.003 |
cEEG duration in hours: median (IQR) | 44.8 (27.3–71.3) | 59.7 (40.4–86.5) | 39.2 (25.3 – 46.5) | <0.0001 |
Anti-epileptic drugs | 89 (62.2%) | 56 (83.6%) | 33 (43.4%) | <0.0001 |
Cerebral edema | 35 (24.5%) | 19 (28.4%) | 16 (21.1%) | 0.34 |
Hemorrhagic transformation | 21 (14.7%) | 10 (14.9%) | 11 (14.5%) | 1.00 |
Hemicraniectomy | 12 (8.4%) | 7 (10.5%) | 5 (6.6%) | 0.55 |
Hospital acquired infections | 63 (44.1%) | 24 (35.8%) | 39 (51.3%) | 0.07 |
Duration of MV(days): median (IQR) | 3 (0–7) | 4 (0–8) | 2 (0–6) | 0.51 |
Length of stay (days): Median (IQR) | 14 (7.5–25) | 14 (8–26) | 14 (7–21.5) | 0.27 |
Discharge mortality | 36 (25.2%) | 20 (29.9%) | 16 (21.1%) | 0.25 |
Withdrawal of care | 33 (91.7%) | 19/20 (95.0%) | 14/16 (87.5%) |
EAs excluding GRDA
APACHE II: Acute Physiology and Chronic Health Evaluation II; CCI: Charlson Comorbidity Index; cEEG: continuous electroencephalography; EAs: epileptiform abnormalities; MV: mechanical ventilation; NIHSS: National Institute of Health Stroke Scale