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. 2020 Aug 3;10:342. doi: 10.3389/fcimb.2020.00342

Figure 1.

Figure 1

Relative reduction of fecal microbial diversity in patients with AIH (N = 37) and HCs (N = 78). (A) Specaccum species accumulation curves for number of samples and estimated richness. Estimated OTU richness approached saturation in all samples. Fecal microbial diversity estimated by Shannon index (B) was significantly decreased in patients with AIH (blue) compared with HCs (red). (C) Venn diagram displaying overlaps between groups showed that 672 of the 874 OTUs were shared between the AIH (blue) and HCs (red) groups. Thirty of the 874 OTUs were unique to AIH. AIH, autoimmune hepatitis; HCs, healthy controls; OTUs, operational taxonomic units. Significant differences by *P < 0.05; **P < 0.01, ***P < 0.001.