Table 1.
Clinical characteristics.
| Characteristics | AIH (n = 37) | HC (n = 78) | P-value |
|---|---|---|---|
| Age, years, median (min–max) | 50 (25–72) | 49.5 (36-65) | 0.469 |
| Gender, Female, n (%) | 34 (91.89%) | 67 (85.9%) | 0.358 |
| BMI, kg/m2, median (min–max) | 21.89 (18.47–29.34) | 22.04 (18.31–29.34) | 0.962 |
| HEPATIC FUNCTION, MEDIAN (MIN–MAX) | |||
| ALT, U/L | 160 (47–553) | 16 (7–38) | 0.000- |
| AST, U/L | 95 (40–407) | 20 (11–33) | 0.000 |
| AKP, U/L | 70 (40–263) | 69 (32–157) | 0.296 |
| GGT, U/L | 90 (54–321) | 17 (7–49) | 0.000 |
| TB, umol/L | 20 (6–71) | 11.305 (3.8–18.12) | 0.000 |
| ALB, g/L | 36 (29–54) | 47.35 (39.6–53.2) | 0.000 |
| IMMUNOGLOBULIN, MEDIAN (MIN–MAX) | |||
| IgG, g/L | 21.3 (9.82–44) | ||
| IgM, g/L | 1.5 (0.51–4.2) | ||
| IgA, g/L | 1.8 (0.6–8.63) | ||
| AUTOANTIBODY, ±, +% | |||
| ANA | 33/4; 89.19% | ||
| ASMA | 5/32; 13.51% | ||
| SLA/LP | 9/28; 24.32% | ||
Continuous variables were compared using Wilcoxon rank sum test between both groups. Fisher's exact test compared categorical variables. Statistical analyses were performed using SPSS version 20.0 for Windows (SPSS Inc., Chicago, IL).
BMI, body mass index; AIH, autoimmune hepatitis; ALT, alanine aminotransferase; AST, aspartate aminotransferase; AKP, alkaline phosphatase; GGT, gamma-glutamyltransferase; TB, total bilirubin; ALB, albumin.