Fig. 1.

HBV genome lengths of each genotype. Standard genome lengths, and sites with deletions and insertions, are illustrated for genotypes A–J, along with a map of the HBV genome layout. Deletions and insertions are shown relative to genotype A, which is widely used as a numbering reference for HBV. Deletions are shown as white gaps and sites of insertions are indicated in black with triangles above them. All genotypes have a 6 bp deletion in the core (C), relative to genotype A (at nucleotide (nt)2354). Genotypes E and G have a 3 bp deletion in the pre-S1 region (at nt2861) and genotypes D and J have a 33 bp deletion at the start of the pre-S1 region (at nt2854) [2]. Genotype G also has a 33 bp insertion in the core (at nt1903).