. 2020 Aug;1(4):e165–e174. doi: 10.1016/S2666-5247(20)30031-8

Table 1.

List of isolate sources including four cohort studies, a randomised clinical trial, and a provincial referral laboratory

	Location	Design	Patients recruited	Sputum collection time points	Number of patients	Number of isolates
PRAXIS (aim 1), NCT03162107 ¹¹	King Dinuzulu Hospital, Durban	Observational cohort study	HIV co-infected, multidrug-resistant or extensively drug-resistant tuberculosis starting bedaquiline	Baseline, month 1, month 2, month 3, month 4, month 5, month 6, end of treatment	76	145
PRAXIS (aim 2), NCT04032730 ¹¹	King Dinuzulu Hospital, Durban	Randomised controlled trial	HIV co-infected, multidrug-resistant or extensively drug-resistant tuberculosis starting bedaquiline	Baseline, month 2, month 6, end of treatment	41	53
Hlabisa DR-TB, unpublished	Hlabisa Hospital, uMkhanyakude District	Observational cohort study	Multidrug-resistant tuberculosis	Baseline	113	113
CUBS (FIND arm), unpublished	King Dinuzulu Hospital, Durban	Observational cohort study	Multidrug-resistant tuberculosis	Baseline, month 2, month 6, end of treatment	64	81
CUBS (PZAP arm), unpublished	Don Mackenzie Hospital, Durban	Observational cohort study	Multidrug-resistant tuberculosis	Baseline, week 1, week 2, week 4, week 6, month 2, month 3, month 4, month 5, month 6, end of treatment	91	256
Provincial referral laboratory isolates	Inkosi Albert Luthuli Central Hospital, Durban	Ad hoc	Extensively drug-resistant tuberculosis	NA	6	28

ClinicalTrials.gov study registration numbers of isolate sources have been added, if available. All isolates were collected in KwaZulu-Natal, South Africa. A total of 676 isolates were collected from 391 patients. NA=not applicable.