TABLE III. Characterisation of best target proteins for Bartonella bacilliformis USMLMMB07.
Gene name | Description | Pi* | Mw** | Subcellular localisation | Molecular function | Biological process |
fabI | enoyl-(acyl carrier-protein) reductase | 5.78 | 29 368.63 | Cytoplasmic membrane | Catalytic activity | Fatty acid biosynthesis process |
folA | dihydrofolate reductase | 6.59 | 18 799.5 | Cytoplasm | NADP binding activity | Metabolic process of a carbon Biosynthetic nucleotide process Biosynthetic process of amide |
aroA | 3-phosphoshikimate carboxyvinyltransferase | 8.50 | 47 559.16 | Cytoplasm | Transferase activity | It is part of the processes of the family of aromatic amino acids, of the biosynthetic process of chorismate |
trmFO | FADH(2)-oxidising methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase | 7.21 | 51 693.32 | Cytoplasm | Flavin adenine dinucleotide binding methyltransferase activity | tRNA Processing |
uppP | undecaprenyl-diphosphatase | 9.2 | 22 650.04 | Cytoplasmic membrane | Catalytic activity | Integral component of the membrane |
murE | UDP-N-acetylmuramoyl-L- alanyl-D-glutamate--2, 6 -diaminopimelate ligase | 6.51 | 52 537.89 | Cytoplasm | Union binding drugs | Cell cycle, regulation of the cell form, biosynthetic process of peptidoglycan, cell division and organisation of the cell wall |
Pi: isoelectric point; Mw: molecular mass.