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. 2020 Aug 3;14:800. doi: 10.3389/fnins.2020.00800

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Copyright © 2020 Sumaroka, Cideciyan, Sheplock, Wu, Kohl, Wissinger and Jacobson.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Prediction of foveal sensitivity (FS) and visual acuity (VA) in the IRD training set group. (A) Foveal region OCT scans from 3 IRD subjects (S23, S3, S24) representing different ONL thicknesses. (B) Comparison of measured FS (M, orange bar) and predicted results by Model I-FS (white bar) and Model II-FS (light orange bar). Yellow bar is FS value calculated by formula extracted from curve fitting (CF-FS). (C) Comparison of measured VA (dark blue bar) and predicted by Model I-VA (white bar) and Model II-VA (light blue bar). Light green bar is VA calculated by a formula extracted from curve fitting (CF-VA). (D–F) are the same as (A–C) but the scans are from 3 IRD subjects (S11, S8, S20) who have visible defects of IS/OS similar to those encountered in some BCM patients. Dashed lines in (B,C,E,F) represent lower boundary of normal range.