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. 2020 Aug 3;14:800. doi: 10.3389/fnins.2020.00800

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Copyright © 2020 Sumaroka, Cideciyan, Sheplock, Wu, Kohl, Wissinger and Jacobson.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Prediction of FS and VA of BCM patients with large deletion mutations. (A) Foveal region OCT scans from four BCM patients (ages 7–13 years). (B) Non-detectable sensitivity at foveal location (orange bar) and predicted results by Model I-FS (white bar) and Model II-FS (light orange bar) as in Figure 1. Yellow bar is sensitivity value calculated by formula extracted from curve fitting (CF-FS). (C) Comparison of measured VA (dark blue bar) and predicted results by Model I-VA (white bar) and Model II-VA (light blue bar). Light green bar is visual acuity calculated by formula extracted from curve fitting (CF-VA). (D–F) are the same as (A–C) but BCM patients are older (ages 18–35 years); dashed lines in (B,C,E,F) represent lower boundary of normal range. Error bars represent RSME for corresponding model.