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. 2020 Aug 3;14:800. doi: 10.3389/fnins.2020.00800

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Copyright © 2020 Sumaroka, Cideciyan, Sheplock, Wu, Kohl, Wissinger and Jacobson.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Prediction of FS and VA of BCM patients with the C203R mutation. (A) Foveal region OCT scans from four BCM patients (ages 13–35 years). (B) Non-detectable sensitivity at foveal location (orange bar) and predicted results by Model I-FS (white bar), Model II-FS (light orange bar), and CF-FS (yellow bar) as in Figures 1, 3. (C) Comparison of measured VA (dark blue bar) and predicted and predicted by Model I-VA (white bar), Model II-VA (light blue bar), and CF-FS (light green bar). (D–F) are the same as (A–C) but BCM patients are older (ages 35–52 years); dashed lines (in B,C,E,F) represent lower boundary of normal range. Error bars represent RSME for corresponding model.