Table 2.
Common MRI findings in selected causes of progressive cognitive impairment
| Neurologic Disease | Common MRI Findings |
|---|---|
| AD | Atrophy affecting the hippocampi, MTLs, and posterior parietal lobesa |
| DLB | Normal MRI or mild, nonspecific atrophy with relative sparing of MTLsb |
| Frontotemporal dementia | Atrophy of frontal and temporal lobesc |
| Vascular cognitive impairment | Multiple bilateral chronic lacunar strokes; white matter hyperintensitiesc |
| Normal-pressure hydrocephalus | Ventriculomegaly; disproportionately enlarged subarachnoid spaced |
Abbreviation: MTLs, medial temporal lobes.
a
Data from Whitwell, J. L. Progression of atrophy in Alzheimer disease and related disorders. Neurotox Res. 2010 18(3-4): 339-346.
b
Data from Yousaf, T., et al. Neuroimaging in Lewy body dementia. J Neurol. 2019 266(1): 1-26.
c
Data from Masdeu, J. C. Neuroimaging of Diseases Causing Dementia. Neurol Clin. 2020 38(1): 65-94.
d
Data from Graff-Radford, N. R. and D. T. Jones. Normal Pressure Hydrocephalus. Continuum (Minneap Minn). 2019 25(1): 165-186.