Table 2.

Prognostic factors for IC, PFS, and OS based on univariate and multivariate analyses.

		IC						PFS						OS
		Univariate			Multivariate			Univariate			Multivariate			Univariate			Multivariate
Factors	Level	P	HR	95%CI	P	HR	95%CI	P	HR	95%CI	P	HR	95%CI	P	HR	95%CI	P	HR	95%CI
Gender	Male
	Female	0.035	0.435	0.2–0.944	0.04	0.443	0.204–0.962	0.084	0.612	0.35–1.068				0.005	0.421	0.232–0.767	0.005	0.381	0.193–0.75
Age, median (IQR)		0.192	0.987	0.969–1.006				0.297	0.992	0.976–1.007				0.579	0.995	0.98–1.012
ECOG	0
	1	0.463	1.257	0.682–2.316				0.381	1.25	0.758–2.062				0.475	1.206	0.722–2.015
Hepatitis B virus	Negative
	Positive	0.503	1.224	0.678–2.21				0.357	1.253	0.775–2.025				0.29	1.303	0.798–2.128
KPS, median (IQR)		0.222	0.98	0.948–1.013				0.058	0.973	0.946–1.001				0.028	0.968	0.941–0.996	0.019	0.965	0.937–0.994
Tbil, median (IQR)		0.669	1.001	0.995–1.007				0.53	1.002	0.997–1.007				0.014	1.006	1.001–1.01	0.418	1.004	0.995–1.013
Albumin, median (IQR)		0.054	0.949	0.899–1.001				0.037	0.954	0.913–0.997	0.464	0.966	0.882–1.059	0.006	0.939	0.898–0.982	0.501	0.948	0.811–1.108
Tumor size, median (IQR)		0.705	1.013	0.948–1.082				0.886	1.004	0.95–1.061				0.516	1.018	0.964–1.076
Urea, median (IQR)		0.913	0.992	0.862–1.142				0.729	0.979	0.87–1.102				0.708	0.978	0.868–1.101
ALP median (IQR)		0.878	1	0.998–1.002				0.191	1.001	1–1.002				0.034	1.001	1–1.002	0.218	1.001	0.999–1.002
PT, median (IQR)		0.651	1.03	0.907–1.169				0.969	1.002	0.899–1.117				0.63	1.028	0.919–1.149
ALBI score, median (IQR)		0.068	1.641	0.964–2.795				0.045	1.574	1.011–2.452	0.931	1.043	0.402–2.705	0.001	2.087	1.347–3.236	0.731	0.735	0.128–4.235
AFP, median (IQR)		0.16	1	43831				0.099	1	43831				0.015	1	1.0–1.0	0.087	1	1.0–1.0
RT dose, median (IQR)		0.094	0.975	0.947–1.004				0.133	0.981	0.957–1.006				0.09	0.978	0.953–1.003	0.073	0.977	0.953–1.002
Tumor number	1	0.93						0.931						0.865
	2	0.749	0.862	0.348–2.136				0.747	0.881	0.409–1.898				0.653	0.828	0.363–1.887
	≥3	0.815	0.92	0.459–1.844				0.823	0.936	0.525–1.67				0.794	1.081	0.604–1.934
Cheng's type of PVTT	I	0.749						0.595						0.308
	IIa	0.921	1.061	0.329–3.419				0.821	0.9	0.362–2.24				0.653	0.811	0.325–2.023
	IIb	0.915	0.906	0.151–5.448				0.373	1.719	0.522–5.665				0.382	1.699	0.517–5.58
	III	0.557	1.431	0.433–4.731				0.938	1.038	0.405–2.662				0.717	0.839	0.325–2.168
	IV	0.472	1.932	0.322–11.609				0.428	1.786	0.425–7.504				0.305	2.125	0.503–8.971
	IVCTT	0.846	0.872	0.218–3.492				0.744	0.836	0.285–2.452				0.452	0.656	0.218–1.97
Child–Pugh	A
	B	0.882	1.061	0.489–2.302				0.472	1.244	0.686–2.258				0.005	2.23	1.269–3.921	0.594	1.259	0.541–2.928
TACE	No
	Yes	0.137	0.709	0.451–1.115	0.164	0.725	0.46–1.14	0.044	0.679	0.466–0.989	0.123	0.735	0.497–1.087	0.003	0.56	0.382–0.821	0.037	0.648	0.43–0.975