Typical elution profiles from each chromatography step
(A and B) Elution profile of recombinant human α1B/β3-tubulin from two 1 mL HisTrap columns (A) and two 1 mL StrepTrap columns (B).
(C) The chromatogram of the flow-through from HiTrap SP/HisTrap HP columns.
(D and E) Elution profile of recombinant human α1B/β3-tubulin (D; peak volume, 81.1 mL) or bovine brain tubulin (E; peak volume, 80.4 mL) from size-exclusion chromatography. *, non-specific instrument singal. V0, void volume. 1CV, one column volume.