Skip to main content
. 2020 Aug 10;16(8):e1008505. doi: 10.1371/journal.pgen.1008505

Fig 5. Immediate transcription of daf-7 is selectively induced by activation of calcium-dependent and calcium-independent pathways in ASJ neurons.

Fig 5

A schematic describing the current model for the sensory transduction pathway in the ASJ neurons resulting in fast neuronal gene transcription in response to P. aeruginosa metabolite phenazine-1-carboxamide (PCN). The model highlights the role of canonical signal transduction pathway molecules as well the added role of the cGMP-dependent kinase EGL-4 as one of the two parallel pathways required for the induction of daf-7. Note that the activation of both pathways are required for the full induction of daf-7.