Table 3. Antimicrobial resistance profile of pathogens isolated from neonates with symptoms and signs of sepsis at Mulago national referral hospital between January and December 2018.
Antibiotics | All participants | Neonates with culture-positive sepsis | S. aureus | E. coli | K. pneumoniae |
---|---|---|---|---|---|
N = 359 (%) | n = 46 (%) | n = 29 | n = 7 | n = 5 | |
Erythromycin | 21 (5.8) | 21 (45.7) | 21(72.4) | NA | NA |
Vancomycin | 0 | 0 | 0 | NA | NA |
Tetracycline | 13 (3.6) | 13 (28.3) | 13 (44.8) | NA | NA |
Penicillin | 28 (7.8) | 28 (60.9) | 28 (96.6) | NA | NA |
Gentamicin | 11 (3.1) | 11 (23.9) | 7(24.1) | 2 (28.6) | 2 (40.0) |
Trimethroprim-Sulphamethoxazole | 34 (9.5) | 34 (73.9) | 27 (93.1) | 4 (57.1) | 3 (60) |
Chloramphenicol | 8 (2.2) | 8 (17.4) | 7 (15.2) | 0 | 1 (2.2) |
Ampicillin | 39 (10.9) | 39 (84.8) | 28 (96.6) | 6 (85.7) | 5 (100.0) |
Amoxycillin-clavulanic acid | 9 (2.5) | 9 (19.6) | NA | 5 (71.4) | 4 (80.0) |
Ceftazidime* | 4 (1.1) | 4 (8.7) | NA | 1 (14.3) | 3 (60) |
Ceftrioxone* | 4 (1.1) | 4 (8.7) | NA | 1 (14.3) | 3 (60) |
Cefuroxime* | 4 (1.1) | 4 (8.7) | NA | 1 (14.3) | 3 (60) |
Imipenem* | 4 (1.1) | 4 (8.7) | NA | 1 (14.3) | 3 (60) |
*The four isolates (resistant to these antibiotics) are the same.