Table 1.
Clinical and laboratory features of patients at last follow-up
| Total | NRF | CKD | Coefficient (95% CI)a | P-value | |
|---|---|---|---|---|---|
| Number of patients, n/N (%) | 93 | 66/93 (71) | 27/93 (29)b | – | – |
| Age (years) | 14 ± 9c | 15 ± 10c | 12 ± 6c | – | 0.16 |
| Kidney assessment, n/N (%) | |||||
| Polyuria | 22/88 (25) | 2/62 (3) | 20/26 (77) | 4.34 (2.95–6.60) | <0.001*** |
| Abnormal kidney ultrasound | 23/85 (27)d | 2/62 (3) | 21/23 (91) | 5.34 (3.72–8.14) | <0.001*** |
| Other features | |||||
| Retinopathy | 33/92 (36) | 17/65 (26) | 16/27 (59) | 1.38 (0.46–2.39) | 0.004** |
| Coloboma | 12/93 (13) | 9/66 (14) | 3/27 (11) | −0.15 (−1.80 to 1.10) | 0.83 |
| Liver involvement | 17/91 (19) | 12/65 (19) | 5/26 (19) | 0.09 (−1.19 to 1.18) | 0.88 |
For each variable, the % is calculated on the effective number of patients for whom information was available.
a
The coefficient stands for the regression coefficient β between renal function and each independent variable; bincluding two patients with iUCD and 25 with decreased eGFR; cvalues are expressed as mean ± SD; dincluding three patients with cystic kidney dysplasia. **P-value ≤0.01; ***P-value ≤0.001.
CKD, chronic kidney disease; NRF, normal renal function.