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. 2020 Aug 4;9:e59153. doi: 10.7554/eLife.59153

Figure 2. Overview of T2D associated lipids.

(A) Volcano plot showed -log10(FDR) against log2(OR) of 816 lipid species in the association with T2D risk. Grey circles were denoted as no significant association with T2D risk. Of those that are significantly associated, red circles denote as neutral lipids, orange as phospholipids, blue as sphingolipids. (B) Number of T2D positive-, negative- and non- associated lipids in each lipid class were shown. Orange, green and blue bars denote positive-, negative- and non- associated lipids respectively. Significance was indicated by FDR < 0.05.

Figure 2—source data 1. Odds ratio, 95% CI and FDR values of all lipids. Lipids with FDR < 0.05 were highlighted.
elife-59153-fig2-data1.xlsx (112.1KB, xlsx)

Figure 2.

Figure 2—figure supplement 1. Supervised PCA indicated partial separability of lipid profiles between case and control groups.

Figure 2—figure supplement 1.

Figure 2—figure supplement 2. Odds ratio and 95% CI of 311 lipids associated with T2D risk (FDR < 0.05).

Figure 2—figure supplement 2.