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. Author manuscript; available in PMC: 2021 Jun 15.
Published in final edited form as: Cancer Res. 2020 Apr 29;80(12):2498–2511. doi: 10.1158/0008-5472.CAN-19-2247

Figure 5. FBXW7 promotes proliferation of mature B-cell neoplasms.

Figure 5.

A,B,C, Plots of cell counts over time. Indicated cells were infected with lentiviruses encoding sgRNAs targeting human FBXW7, KMT2D or combination (n=3; mean ± SD; two-way ANOVA (*p<0.05, **p<0.01, ***p<0.001, ****p<0.0001)). D, Tumor volume measurement over time from xenografts of U2932 cells that were subcutaneously injected into NSG mice flanks (n=4; mean ± SD; two-way ANOVA (*p<0.05, **p<0.01, ***p<0.001, ****p<0.0001)). E, Weights of tumors excised from (d) at end-point (n=4, mean ± SD, two-tailed Student’s t-test*p<0.05). F, Pictures of tumors from (d).