Table 4.

Comparison of electrocardiographic findings during treatment course.

Parameters	∆1. on-treatment ECG vs. baseline ECG	P value	∆2. on-treatment vs. ∆1. on-treatment ECG	P value	∆2. on-treatment ECG vs. baseline ECG	P value
Heart rate, bpm, mean ± SEM	10 ± 1	< 0.001	1 ± 1	0.4	10 ± 1	<0.001
RR duration, ms, mean ± SD	62.53 ± 9.42	<0.001	14.47 ± 14.17	0.29	77 ± 24.95	0.009
PR interval, ms, mean ± SD	−2.12 ± 18.90	0.65	−0.82 ± 9.79	0.73	−2.94 ± 19.93	0.55
QRS duration, ms, mean ± SEM	3.88 ± 8.37	0.074	1.29 ± 8.51	0.54	5.18 ± 8.94	0.03
QTc interval, ms, mean ± SEM •by Bazett •by Frederica •by FHS	24.40 ± 2.99 26.64 ± 3.12 28.90 ± 2.97	<0.001 <0.001 < 0.001	−17.76 ± 3.94 −15.96 ± 3.94 −14.76 ± 3.65	<0.001 0.001 0.001	6.64 ± 9.60 10.67 ± 9.9 14.14 ± 9.68	0.5 0.19 0.16

SD- standard mean; SEM- standard error of mean;

*minus “- “indicates shortened duration. ^†Bold indicates statistically significant value. SE.