Table 4.
Binary logistic regression model for normal cognition vs. cognitive impairment (PD-MCI/PDD).
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| Crude OR | 95% CI | p | Adjusted OR | 95% CI | p | |
| Sex (women) | 1.17 | 0.67–2.04 | 0.56 | 1.51 | 0.74–3.09 | 0.255 |
| Age | 1.07 | 1.04–1.10 | <0.001 | 1.01 | 0.97–1.05 | 0.411 |
| Age at onset | 1.02 | 0.99–1.05 | 0.148 | – | – | – |
| Years of education | 0.84 | 0.79–0.90 | <0.001 | 0.9 | 0.83–0.98 | 0.013 |
| Disease duration | 1.18 | 1.10–1.27 | <0.001 | 1.07 | 0.96–1.18 | 0.204 |
| Hoehn and Yahr | 4.28 | 2.94–6.23 | <0.001 | 2.06 | 1.10–3.85 | 0.022 |
| Barthel Index | 0.9 | 0.87–0.94 | <0.001 | 0.94 | 0.90–0.97 | 0.002 |
| SMS-Motor examination | 1.19 | 1.13–1.25 | <0.001 | 1.11 | 1.01–1.21 | 0.019 |
| SMS-ADL | 1.31 | 1.21–1.42 | <0.001 | 0.86 | 0.72–1.03 | 0.101 |
| SMS-Motor complications | 1.29 | 1.16–1.42 | <0.001 | 0.87 | 0.72–1.04 | 0.137 |
| SCOPA-PC | 1.04 | 0.98–1.10 | 0.199 | – | – | – |
| Hallucinations* | 5.6 | 1.95–16.04 | 0.001 | 1.57 | 0.41–5.99 | 0.504 |
| HADS, Anxiety | 1.17 | 1.09–1.25 | <0.001 | 1,00 | 0.89–1.13 | 0.904 |
| HADS, Depression | 1.21 | 1.12–1.30 | <0.001 | 1.07 | 0.95–1.21 | 0.213 |
OR, odds ratio; CI, confidence interval; SMS, Scales for Outcomes in Parkinson's disease-Motor Scale; ADL, activities of daily living; SCOPA-PC, Scales for Outcomes in Parkinson's disease-Psychiatric Complications; HADS, Hospital Anxiety and Depression Scale.
*
Hallucinations: item from SCOPA-PC. Bold indicates the significant values.