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. 2020 Aug 4;11:1720. doi: 10.3389/fimmu.2020.01720

Figure 2.

Figure 2

Administration of XCL1 exaggerates osteolytic lesions in a polyethylene-particles-induced osteolysis model. (A) Representative images for micro-CT of calvariae. The right panel shows quantification of the lytic area on the calvarial bone tissues of mice. Results represent the means ± SEM of seven mice. *represents the significance determined by one-way ANOVA, followed by a Tukey's multiple-comparison procedure. Arrows indicate osteolytic lesions. (B) Representative images for histological analyses of bone sections stained by H&E and TRAP. Scale bar is 100 μm. Arrows indicate bone lesions. (C) Cell count of inflammatory cells in calvarial bone sections. (D) Quantification of TRAP-stained areas in calvarial bone sections. The results represent the means ± SEM for three mice. *indicates a significant difference, as determined by one-way ANOVA, followed by the Tukey's multiple-comparison procedure (p ≤ 0.05).