Figure 4.

Heat map representing the increased fold changes of cytokine concentration in culture supernatants of total isolated cells from the FRT compartments and PBMC stimulated with TLR7/8, TLR3, TLR4, and TLR9 agonists at 72 h. Uterus n = 7, Endocervix n = 6, Ectocervix n = 10, Vagina n = 7, and PBMC n = 6. A Wilcoxon single-rank test was performed: *p < 0.05, **p < 0.01, and ^§p < 0.0001. Each case represents the median of fold change for one compartment for one cytokine. Only increased fold changes ≥1.2 are represented.