Figure 1.

EV-mediated cross talk in the lung microenvironment. The lung microenvironment is characterized by a complex cross talk of several different cell types. Secreted extracellular vesicles (EV) from these cells have been shown to play critical roles in the tissue homeostasis or the development of chronic respiratory disease due to the transfer of molecules to other cell types. EVs are displayed in the respective color of the parent cell, and transferred molecules are indicated next to the arrows.