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. 2020 Aug 4;11:1719. doi: 10.3389/fimmu.2020.01719

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Copyright © 2020 Locke, Schlesinger and Crouser.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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M.tb antigen stimulation induces a unique and divergent transcriptional response in sarcoidosis. Differential gene expression in PBMCs derived from patients with sarcoidosis and healthy control subjects after (A) uncoated and (B) M.tb antigen-coated bead stimulation shown as mva style plots. The x-axis is the log2 average of the gene expression level. All genes with an adjusted P-value of 0.05 and at least a log2-fold change in the magnitude of gene expression (indicated by the two horizontal blue lines) between M.tb antigen and uncoated beads are shaded red.