Table 1.

Binding^a of C3b by different regions of Factor H.

Factor H domains	Kd (μM)b	Factor H domains	Kd (μM)b
CCP 1-6	0.08 ± 0.04	CCP 16-20	2.4 ± 0.3
CCP 1-7	0.08 ± 0.02	CCP 17-20	2.1 ± 0.2
CCP 1-8	0.15 ± 0.01	CCP 18-20	1.9 ± 0.3
CCP 6-15	15 ± 2.0	CCP 19-20	1.7 ± 0.3
CCP 6-12	NDBc	CCP20	NDBc

^aBinding data was generated as in Figure 3 and K_d values were determined as in Figure 4 for the recombinantly generated Factor H fragments indicated.

^bStandard errors from non-linear regression analysis are reported.

^cNDB indicates “No Detectable Binding” was observed.