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. 2020 Aug 4;14:72. doi: 10.3389/fncom.2020.00072

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Copyright © 2020 Bingham, Paknahad, Girard, Loizos, Bouteiller, Song, Lazzi and Berger.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Synthesis of feedforward AM-NEURON methods demonstrated in Bingham et al. (2018a) and feedback AM-NEURON examined in this manuscript via current (A) splitting and (B) shifting yields an algorithm for bidirectional communication in mechanistic models of neural tissue systems and volume conduction models. The above pseudocode would be the same for tetrahedral geometry except for the substitution of the number of nodes to interpolate from (4 vs. 8) in A. Except in very coarse meshes, shifting (a simpler algorithm) produced results comparable to current splitting in hexahedral or tetrahedral models.