Table 4.
Mean Follow-Up 6MWT Distance and Total SGRQ Score by COPD Treatment Classification
| Outcome by Exposure | 2017 Groups A and B |
2017 Groups C and D |
||
|---|---|---|---|---|
| Crude β1 Coefficient (95% CI) | Adjusted β1 Coefficienta (95% CI) | Crude β1 Coefficient (95% CI) | Adjusted β1 Coefficientb (95% CI) | |
| Follow-up 6MWT (m) | ||||
| Aligned | Referent | Referent | Referent | Referent |
| Undertreated | 9 (−3 to 15) | 12 (2 to 22) | 7 (−14 to 29) | 7 (−23 to 37) |
| Overtreated | 6 (0 to 19) | 6 (−3 to 15) | −8 (−31 to 16) | −23 (−53 to 8) |
| Follow-up SGRQ score | ||||
| Aligned | Referent | Referent | Referent | Referent |
| Undertreated | −1.1 (−2.9 to 0.6) | −1.1 (−3.1 to 0.9) | −0.5 (−3.2 to 2.3) | −0.3 (−3.2 to 2.7) |
| Overtreated | 0.2 (−1.0 to 1.5) | 0.2 (−1.1 to 1.5) | 0.1 (−3.6 to 3.9) | 0.3 (−3.7 to 4.3) |
See Table 1 legend for expansion of abbreviations.
Multivariable linear regression model with an exchangeable correlation matrix linked on patient identity, adjusted for baseline 6MWT distance, age, sex, Charlson comorbidity index score, smoking status, BODE index, Global Initiative for Chronic Obstructive Lung Disease stage, and site. A total of 572 patients had at least one outcome measure.
Multivariable linear regression model with an exchangeable correlation matrix linked on patient identity, adjusted for baseline SGRQ score, age, sex, Charlson comorbidity index score, smoking status, BODE index, Global Initiative for Chronic Obstructive Lung Disease stage, and site. A total of 645 patients had at least one outcome measure.