Fig. 1.

Allicin enhances the sensitivity of U251-TR cells to TMZ. a, b Effects of TMZ on U251-TR and parental U251 cells viability. U251-TR and parental U251 cells were treated with different concentrations (0, 10, 20, 50, 100, and 200 μg/ml) of TMZ for 24, 48, or 72 h. *P < 0.05, **P < 0.01 versus control group (0 μg/ml). c, d Effects of Allicin on U251-TR and parental U251 cells viability. U251-TR and parental U251 cells were treated with different concentrations (0, 10, 20, 30, 40, and 50 μg/ml) of Allicin for 24, 48, or 72 h. *P < 0.05, **P < 0.01 versus control group (0 μg/ml). e, f U251-TR and parental U251 cells were treated with 30 μg/ml Allicin: 50 μg/ml TMZ, 30 μg/ml Allicin + 50 μg/ml TMZ for 24, 48, or 72 h. *P < 0.05, **P < 0.01. Data are mean ± SEM of cell viability from three independent experiments with triplicates in each experiment