Table 2.
Patient baseline characteristics by age group
| Age, year | n | Sex | Racea | ECOG PSb | Median body weight (range), kg | Median BSA (range), m2 | |||
|---|---|---|---|---|---|---|---|---|---|
| M | F | Asian | Non-Asian | 0 | > 0 | ||||
| 2–5 | 6 | 3 | 3 | 1 | 5 | 2 | 1 | 18.3 (16.2–28.7) | 0.69 (0.66–0.98) |
| 6–11 | 20 | 9 | 11 | 0 | 18 | 8 | 4 | 28.4 (17.1–56.3) | 1.10 (0.72–1.48) |
| 12–17 | 27 | 11 | 16 | 1 | 25 | 12 | 15 | 60.4 (37.1–100) | 1.63 (1.27–2.14) |
| 18–21 | 6 | 3 | 3 | 1 | 5 | 1 | 5 | 71.3 (62.5–74.5) | 1.87 (1.62–1.92) |
| Total 2–21 | 59 | 28 | 31 | 3 | 53 | 23 | 25 | 50.4 (16.2–100) | 1.47 (0.66–2.14) |
ECOG PS Eastern Cooperative Oncology group performance status, F female, M male
aRace was unknown for three patients
bECOG PS scores based on either ECOG PS or extrapolated from Karnofsky performance scale, with ECOG PS set to 0 and 1 for Karnofsky performance scale > 90 and ≤ 90, respectively. ECOG PS could not be determined for 11 patients