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. 2019 Oct 18;42(3):275–282. doi: 10.1016/j.htct.2019.07.010

Fig. 2.

Fig. 2

Shows the pathophysiology of the mechanism of action of ASNase. The figure above shows the normal functioning of ASNase degrading asparagine and leading to cell death. And the figure below shows the silent inactivation situation where antibody production leads to low or loss of ASNase activity.