Table 3.

Multiple Proportional transition hazards models.

Path	Variable	β	HR	Z statistic	P-value
Disease → Local relapse	Site of tumor1: Rectum	-0.37	0.69	-1.24	0.214
	Stage2: I/II	-0.79	0.45	-2.44	0.014
	Marital status3:married	-0.59	0.55	-0.95	0.344
	Divorced / widow	-0.47	0.63	-0.55	0.582
	Family history of cancer4: No	-0.29	0.75	-0.89	0.376
	Addiction5: No	-0.19	0.82	-0.44	0.659
	Age6: >50 years	-0.18	0.83	-0.62	0.538
	BMI7 (kg/m2):18.5-25	0.17	1.18	0.44	0.658
	25-30	-0.60	0.55	-1.05	0.293
	>30	0.21	1.24	0.37	0.711
Disease → Death due to metastasis	Type of first treatment8: neoadjuvant chemotherapy	0.24	1.28	0.95	0.344
	Stage2: I/II	-1.44	0.24	-4.56	<0.001
	Ethnicity9: Non-Fars	0.99	2.71	3.06	0.002
	Family history of cancer4: No	0.54	1.72	1.53	0.127
	Addiction5: No	-0.52	0.59	-1.38	0.168
	Age6: >50 years	0.76	2.15	2.46	0.013
	BMI7(kg/m2):18.5-25	0.13	1.14	0.39	0.698
	25-30	-0.77	0.46	-1.51	0.131
	>30	0.23	1.25	0.43	0.668
Local relapse → Death due to metastasis	Type of first treatment8: neoadjuvant chemotherapy	0.81	2.25	1.81	0.070
	Stage2: I/II	0.68	1.98	1.33	0.182
	BMI7(kg/m2): 18.5-25	-1.16	0.31	-1.97	0.048
	25-30	-2.67	0.07	-2.28	0.022
	>30	-1.77	0.17	-2.14	0.032

Reference categories: ¹ colon, ² III/IV, ³ single ⁴ yes, ⁵ yes, ⁶ <=50, ⁷ <18.5 kg/m² , ⁸ surgery , ⁹ Fars