Table 4.

Multivariate logistic regression analysis to analyze the factors affecting neutropenia at first and second cycles.

Factors	First cycle			Second cycle
	Grade 1–4 neutropeniaa			Grade 1–4 neutropeniaa			Grade 3–4 neutropeniab
	Exp (B)	95% CI	P value	Exp (B)	95% CI	P value	Exp (B)	95% CI	P value
ABCC2 3972C > T	5.06	1.38–18.63	0.015†
UGT1A1 *28 (A(TA)7TAA)				5.44	1.48–20.02	0.011†
UGT1A1*6 (211G > A)				30.67	3.51–268.36	0.002†	12.50	2.73–57.29	0.001†

Exp exponential, 95% CI 95% confidence interval.

^†p value < 0.05 was considered statistically significant.

^aGrade 1–4 was considered as toxicity.

^bGrade 3–4 was considered as severe toxicity.