Figure 2.

Unaltered ion channel distribution in the axo-myelinic junction of the CNS of ngr1^−/− mice. Schematic representation of the proposed ion channel distribution in the CNS myelinated fibers of wild-type, ngr1^−/− and caspr^−/− mice. In caspr^−/−, juxtaparanodal Kv channels are displaced and distributed throughout the paranodal region, whereas in ngr1^−/−, although lengthening of paranodal Caspr was found, ion channel distribution could not be identified (Lee et al., 2017).