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. 2020 Aug 4;11:853. doi: 10.3389/fgene.2020.00853

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Copyright © 2020 Liu, Zhu, Ho, Shi, Li, Wang, Chan and Cheng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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miR-430 is required for the degradation of maternally provided transcripts and activation of zygotic gene expression. (A) Schematic representation of the expression profiles of miR-430-regulated genes during MZT (64/128-cell stages, oblong and 50 epiboly). The miR-430-regulated genes were grouped into three categories based on their expression profiles. The expression profiles of genes in the control set (B), up-regulated set (C), and down-regulated set (D) of the miR-430 mutants during MZT.