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. 2020 Aug 4;14:51. doi: 10.3389/fnsys.2020.00051

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Copyright © 2020 Yang, Zhan, Lin, Chu, Qiu and Lan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Fentanyl depresses air-puff stimulation-evoked responses in cerebellar molecular layer interneurons (MLIs). (A) Upper, an example of cell-attached recording from an MLI showing responses to air-puff stimulation (60 ms, 60 psi) in ACSF, and fentanyl (5 μM); lower, raster plot of spike events originating from traces in the upper panel. (B) Summarized results showing the normalized frequency of spontaneous firing in ACSF, fentanyl (5 μM, n = 6). (C) Summarized results showing the normalized frequency of tactile-evoked firing in ACSF and fentanyl (5 μM, n = 6). *P < 0.05 vs. ACSF group.