FIGURE 6.

Differential G6Pase expression predicts outcomes in 322 ccRCC patients from FUSCC cohorts. A, G6Pase was detected high expressed in normal kidney tissues (specifically in tubules cells rather than glomeruli cells), while not detected in ccRCC tissues from the Human Protein atlas. B, Significantly elevated G6Pase expression was found in normal tissues compared with ccRCC tissues from FUSCC cohort. C‐D, Low G6Pase expression was significantly correlated with poor prognosis (P < 0.0001, HR = 0.316) and aggressive progression (P < 0.0001, HR = 0.414) in 322 ccRCC patients from FUSCC cohort. ccRCC, clear cell renal cell carcinoma; FUSCC, Fudan University Shanghai Cancer Center